.frame {
    position: absolute;
    top: 50%;
    left: 50%;
    width: 400px;
    height: 400px;
    margin-top: -200px;
    margin-left: -200px;
    border-radius: 2px;
    box-shadow: 4px 8px 16px 0 rgba(0,0,0,0.1);
    overflow: hidden;
    background: lightblue;
    color: #333;
    font-family: 'Open Sans', Helvetica, sans-serif;
    -webkit-font-smoothing: antialiased;
    -moz-osx-font-smoothing: grayscale;
}

.center {
    position: absolute;
    top: 25%;
    left: 25%;
    transform: translate(-50%,-50%);
}

.circle {
    left: 25px;
    top: 25px;
    position: absolute;
    border-radius: 50%;
    background: white;
    box-shadow:  4px 8px 16px 0 rgba(0,0,0,0.5);
    animation: ripple 2s cubic-bezier(.21,.98,.6,.99) alternate infinite;
}

.one {
    left:0;
    top: 0;
    width: 200px;
    height: 200px;
    background: black;
}
.two {
    width: 150px;
    height: 150px;
    background: blue;
}
.three {
    width: 100px;
    height: 100px;
    background: red;
}
.four {
    width: 50px;
    height: 50px;
    background: yellow;
}

@keyframes ripple {
    0% {
        transform: scale(0);
    }
    100% {
        transform: scale(1);
    }
}